Drugs Spiked in Different Substances
The following material was derived from a Federal goverment web site (DEA). These warnings are important to everyone, but for anyone arrested for DUI-DWI who has a blood or urine sample taken (for suspected drug usage), these "spiked" medicines could result in a conviction for "D.U.I. drugs". NEVER purchase medications on the street. Invisible layers of powerful drugs (such as LSD) could be present.
In many
states, a defense of "I was not aware that the pill I took contained XYZ
drug" will not guarantee an acquittal or even constitute a valid
defense.
William C.
Head
Atlanta, GA
- INTELLIGENCE ALERT -
70,000 PSILOCYBIN MUSHROOM/CHOCOLATE CANDIES SEIZED NEAR AMARILLO, TEXAS
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Photo 1 |
Photo 2 |
The Texas
Department of Public Safety Crime Laboratory Service in Amarillo
(Amarillo, Texas) recently received a submission of approximately 70,000
chocolate candies (total net mass 154 kilograms), suspected psilocybin
mushroom/chocolate concoctions. The exhibits were seized by the
Texas State Highway Patrol pursuant to a vehicle stop on I-40, just west
of Amarillo (the vehicle was travelling from California to Tennessee). The
candies were being stored in the vehicle's trunk in trash bags, under what
appeared to be a space blanket, and were furthermore being cooled by dry
ice (see Photos 1 and 2). There were two, rather
indistinct designs - a fish, and a cameo (see Photos 3 and 4).
There were two, rather indistinct designs - a fish, and a cameo. Microscopic examination of a crushed sample revealed a large
amount of finely ground, mushroom-like material mixed into the chocolate. Analysis of this material by TLC, UV, and GC/MS confirmed psilocin (quantitation not performed). This was the laboratory's first encounter with psilocybin mushroom/chocolate candies, and in fact was the first encounter with any adulterated form of psilocybin mushrooms. The laboratory's largest previous submission of psilocybin mushrooms was just over seven kilograms.
[Editor's Notes: This appears to be the largest seizure of psilocybin mushroom/chocolate concoctions ever reported. The phenomenon of psilocybin mushroom/chocolate concoctions was discussed at length in the June, 2003 issue of Microgram Bulletin (with additional reports also being published in the May, August, and October 2003 issues of Microgram Bulletin). A specialized forensic analysis for these concoctions was published in Microgram Journal 2003;1(3-4):177.]
- INTELLIGENCE ALERT -
VIAGRA® MIMIC TABLET
CONTAINING AMPHETAMINE IN FEJER COUNTY,
HUNGARY
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Photo 5 |
The
Institute for Forensic Sciences National Drug Laboratory (Budapest,
Hungary) recently received 9,000 white Ecstasy tablets with a "Euro" logo
(see Photo 5), and also one pink, rhombus shaped tablet,
net mass 0.30 gram, with a Pfizer imprint on one side and a VGR50 imprint
on the other side (see Photos 6 and 7), an apparent
Viagra® counterfeit. The exhibits were seized pursuant to a vehicle search
by the County Police in Fejer County, Hungary (located approximately 70
kilometers west of Budapest). Except for the color, the tablet appeared to
be a standard tablet of Viagra (genuine Viagra tablets are blue (see
authentic tablet in Photos 6 and 7, below)). Analysis by
GC/MS and HPLC, however, indicated not sildenafil citrate (Viagra) but
rather 15 milligrams of amphetamine (isomer and salt form not reported).
Analysis of the suspected Ecstasy tablets confirmed MDMA (no further
details). Although the laboratory has previously encountered genuine Viagra
tablets in seizures of Ecstasy, this was the first submission of a Viagra
mimic tablet containing amphetamine.
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Photo 3 |
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Photo 4 |
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Photo 6 |
Photo 7 |
[Editor's Notes:
Viagra is often sold in conjunction with MDMA in order to help users
compensate for the reduced sexual performance that is a common side-effect
resulting from abuse of MDMA. This appears to be the first ever report of
a counterfeit Viagra tablet to Microgram Bulletin.]
- INTELLIGENCE ALERT -
LOLLIPOPS CONTAINING9- TETRAHYDROCANNABINOL AND
PHENCYCLIDINE IN CHICAGO, ILLINOIS
The
Illinois State Police Forensic Science Center at Chicago (Chicago,
Illinois) recently received two submissions containing a total of 55
lollipops, suspected to contain a controlled substance, possibly MDMA,
THC, or GHB. The lollipops were being sold on the West Side of Chicago,
and were seized by the Chicago Police Department. Analysis was prioritized
because the items were apparently being marketed to children. Each
lollipop weighed approximately 10 grams, and were either green, red, or
amber colored, and were in the shape of a maple leaf (see Photo 8)
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Photo 8 |
Photo 9 |
or an
indistinct face resembling Santa Claus (see Photo 9,
above). No visible plant material was observed; however, a
crushed portion tested positive for
tetrahydrocannabinol (THC) with the Duquenois Levine
test. Analysis by GC and GC/MS indicated a mixture of THC and
phencyclidine (PCP) (quantitation not performed). This was the
laboratory's first submission of this type.
- INTELLIGENCE
ALERT -
LARGE ELECTRONIC
CAPACITORS CONTAINING HEROIN IN PHILADELPHIA,
PENNSYLVANIA
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Photo 10 |
The DEA Northeast
Laboratory (New York, New York) recently received a submission of nine
large capacitors, each containing a tan powder, suspected heroin (see
Photo 10). The capacitors were originally attached to a
circuit board (nominal purpose unknown), that had been shipped as air
freight from Venezuela to Philadelphia, Pennsylvania, that was seized by
Immigration and Customs Enforcement Inspectors from the Philadelphia
Office. Analysis of the powder (total net mass 493.7 grams) by GC/FID,
GC/MS, and FTIR confirmed 80 percent heroin hydrochloride. This was the
first submission of this type to the laboratory; however, two additional
circuit boards with capacitors containing heroin have been received since
this initial encounter.
- INTELLIGENCE ALERT -
ONCE REMOVED® NAIL POLISH REMOVER (CONTAINING GBL) SEIZED IN METAIRIE,
LOUISIANA
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Photo 11 |
The DEA South Central
Laboratory (Dallas, Texas) recently received a submission of two bottles
of "Once Removed" nail polish remover and treatment, each containing 30
milliliters of a clear, oily liquid, submitted as unknowns (see
Photo 11). Although the packaging appears to be
professional, the labelling does not list the ingredients, company name,
or company contact information. The DEA New Orleans office seized the
exhibits at a suspected gamma-hydroxybutyric acid (GHB)
clandestine laboratory in Metairie, Louisiana. Analysis of the liquid by
HPLC and GC/MS indicated gamma- butyrolactone (GBL) (not
quantitated, but apparently pure or nearly pure). The laboratory was
apparently a prescription drug diversion operation, re-selling various
substances over the Internet. There were about a dozen empty bottles of
"Once Removed" at the site; the operators were allegedly diluting one
bottle into a one liter bottle of Fruit Punch flavored Powerade for
resale. While GBL is not an uncommon submission to the laboratory, this is
the first exhibit of "Once Removed" nail polish remover.
[Editor's Notes:
"Once Removed" is a product of SMS Laboratories in Brooklyn, New York, and
is very well known in the GHB abusing community as a source of high purity
GBL. The above seizure is unusual because neither the company or product
ingredients are listed on the packaging. It is unknown why this
information was not included on the packaging in this case.]
- INTELLIGENCE
ALERT -
NESTLE SUPLIGEN® CANS CONTAINING LIQUID COCAINE IN
PLANTATION, FLORIDA
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Photo 12 |
The DEA Southeast
Laboratory (Miami, Florida) recently received seven commercially labelled
cardboard boxes containing 288 cans of Nestle's Supligen® (a dietary
supplement drink), suspected to contain solutions of cocaine (see
Photo 12). The exhibits were seized from a storage
facility in Plantation by agents from the DEA Fort Lauderdale District
Office (Plantation is located just west of Fort Lauderdale). Ninety two of
the cans contained a thick, clear liquid (total net mass 38.66 kilograms
(total net volume 31.69 liters)) that screened positively for cocaine.
Analysis by GC, FTIR, and GC/MS confirmed a mixture of cocaine
hydrochloride (753 mg/mL) and phenacetin (not quantitated). This was the
first submission of liquid cocaine in cans of Supligen to the
laboratory.
- INTELLIGENCE ALERT -
LOLLIPOPS CONTAINING HEROIN IN NEW YORK, NEW YORK
The DEA
Northeast Laboratory (New York, New York) recently received a submission
of thirty one lollipops with loose wrappers, suspected to contain heroin
(see Photo 13, below). The exhibits were seized at
LaGuardia airport by the DEA New York Field Division (circumstances not
provided). The wrappers indicated only the flavor of the candy (peach,
watermelon, sour, etc.) The pops varied from 3/4's of an inch to one inch
in diameter, and (unusually) consisted of a candy shell surrounding a
powder interior (see Photo 14, below). Analysis of the
powder (total net mass 520.1 grams) by GC/FID, GC/MS and FTIR confirmed 64
percent heroin hydrochloride. This is the first submission of lollipops
containing heroin powder to the laboratory; however, the laboratory has
previously received lollipops containing cocaine hydrochloride.
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Photo 13 |
Photo 14 |
- INTELLIGENCE ALERT -
SENTRON® FIRE EXTINGUISHERS
CONTAINING COCAINE IN NOGALES, ARIZONA
The DEA
Southwest Laboratory (Vista, California) recently received a submission of
six small Sentron® fire extinguishers, each containing a packed white
powder, suspected cocaine (see Photos 15 and 16, below).
The exhibits were seized from three different cars in Nogales by Agents
from the DEA Tucson Resident Office. The cannisters were labeled in
Spanish, and the pressure gauges indicated that the extinguishers were at
least partially full; however, none were actually under pressure. The
nozzle portions on all six cannisters could be unscrewed; however, removal
of the contents required a power saw to cut the cannister open. Analysis
of the powder (total net mass approximately 12 kilograms) by GC, IR, and
MS confirmed cocaine hydrochloride (average purity approximately 90
percent). This was the laboratory's first encounter with this particular
smuggling technique.
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Photo 15 |
Photo 16 |
- INTELLIGENCE ALERT -
OKLAHOMA FIRST STATE
TO BAN OVER-THE-COUNTER SALES OF PSEUDOEPHEDRINE
TABLETS
[From
the NDIC Narcotics Digest Weekly 2004;3(17):3 Unclassified,
Reprinted with Permission.]
On April 6, 2004, the
governor of Oklahoma signed into law a bill prohibiting over the counter
sales of tablets containing pseudoephedrine, a precursor chemical used in
the production of methamphetamine. The law designates cold and allergy
tablets containing pseudoephedrine as a Schedule V substance that can be
sold only by licensed pharmacists or licensed pharmacy technicians.
Consumers will be required to present valid photo identification and sign
a logbook to purchase the drugs. The law also limits the amount a person
can buy or possess to 9 grams (approximately 10 boxes of cold tablets).
Any person convicted of violating the provisions of the law faces up to 1
year in jail and/or a $1,000 fine for a first offense (misdemeanor) and a
$5,000 fine and a term of imprisonment of not more than 5 years for a
second offense (felony). Consumers will still be able to purchase gel cap
and liquid forms of the drugs over the counter.
NDIC
Comment: Other states, including Missouri and Iowa, have enacted
legislation designed to restrict grocery and discount store sales of
pseudoephedrine products by requiring that the drugs be placed behind the
counter or within sight of clerks. However, Oklahoma is the first state to
ban sales of cold and allergy tablets with pseudoephedrine in stores other
than pharmacies and to control the sale and the amount of the sale of such
products.
- INTELLIGENCE ALERT
-
LOLLIPOP-SHAPED
FENTANYL PRODUCTS DIVERTED IN EASTERN
PENNSYLVANIA
[From
the NDIC Narcotics Digest Weekly 2004;3(20):1 Unclassified,
Reprinted with Permission.]
Law enforcement
officials with the Philadelphia Division of the Drug Enforcement
Administration (DEA), Philadelphia Police Department, and Carbondale
Police Department report increasing diversion and distribution of a
prescription pain reliever known as ACTIQ (oral transmucosal fentanyl
citrate). ACTIQ contains a form of fentanyl a synthetic opiate that
possesses an analgesic potency approximately 80 times stronger than
morphine. The U.S. Food and Drug Administration (FDA) approved ACTIQ in
November 1998 for the management of cancer pain for patients with
malignancies who had already received and had become tolerant to opioid
therapy. ACTIQ, one of several fentanyl products available by
prescription, is distributed as a medicated raspberry flavored lozenge
attached to a short handle resembling a lollipop. As the medicated lozenge
dissolves, the active ingredient (fentanyl citrate) is absorbed through
the lining of the mouth. ACTIQ is intended only for those already on an
opioid based pain management program.
NDIC
Comment: The diversion and abuse of ACTIQ likely will increase
because of individuals seeking the effects of its active ingredient,
fentanyl citrate. The lollipop like administration of the drug is likely
to appeal to users who would be hesitant to take a fentanyl tablet, snort
fentanyl powder, or inject the drug. Moreover, other fentanyl products,
particularly a fentanyl transdermal patch known as Duragesic, already is
frequently diverted and abused in many areas. In fact, National Drug
Threat Survey 2003 data indicate that 10.2 percent of law enforcement
agencies responding nationwide report that fentanyl is commonly diverted
and illicitly used in their areas. Law enforcement agencies in the
Northeast/Mid Atlantic (12.0%), Pacific (11.6%), and West Central (10.9%)
regions report the highest percentages of fentanyl diversion and abuse.
DEA officials in Philadelphia report that ACTIQ, referred to as
perc-a-pop, is being sold in the city for $20 per dosage unit.
[Editor's Note: For a
photo of an ACTIQ lollipop, see: Microgram Bulletin
2004;37(3):49.]
- INTELLIGENCE ALERT
-
MDMA LABORATORY
SEIZED IN MARION [SOUTH DAKOTA]
[From
the NDIC Narcotics Digest Weekly 2004;3(20):3 Unclassified,
Reprinted with Permission.]
On April 27, 2004,
officials from the DEA Sioux Falls Resident Office and Sioux Falls Police
Department Drug Task Force seized an operational MDMA laboratory from a
Marion residence and arrested a 39 year old female and a 25 year old male
on charges of attempting to manufacture MDMA and aiding and abetting the
manufacture of MDMA. The arrests and seizure were the result of a 3 month
investigation conducted to determine the identity of the intended
recipients of chemicals being sent to a Sioux Falls post office box. The
defendants allegedly purchased chemicals and glassware to manufacture MDMA
(3,4-methylenedioxymethamphetamine, also known as ecstasy) through a fictitious
company via the Internet and by telephone from companies in California,
North Carolina, Ohio, Texas, and the Netherlands. The chemicals, including
ether and sassafras oil, and glassware were delivered to the post office
box in Sioux Falls. Prior to their arrests, the defendants allegedly
produced three batches of MDMA, each weighing approximately 4 grams.
According to law enforcement officials, the powdered MDMA was placed in
capsules and distributed to individuals at rave parties in Midwest cities
such as Chicago and Kansas City for $20 $25 per capsule. Law enforcement
officials also seized 4 grams of MDMA, psilocybin mushrooms, marijuana,
and $2,500 from the Marion residence. The DEA, Sioux Falls Police
Department Drug Task Force, South Dakota Highway Patrol, Turner County
Sheriff's Office, U.S. Postal Inspection Service (USPS), Bureau of
Alcohol, Tobacco, Firearms, and Explosives (ATF), Mitchell Police
Department, and Yankton Police Department participated in the
investigation.
NDIC Comment:
Law enforcement officials in South Dakota report that this is the
first MDMA laboratory seizure in the state. Very few MDMA laboratories are
seized each year in the United States. According to DEA El Paso
Intelligence Center (EPIC) National Clandestine Laboratory Seizure System
data, law enforcement agencies report 3 domestic MDMA laboratory seizures
in 2003 compared with 10 seizures in 2002. In 2003 law enforcement
officials seized 1 MDMA laboratory each in Florida, Louisiana, and
Texas.
- INTELLIGENCE BRIEF
-
DIPROPYLTRYPTAMINE
AND 2C-I IN PORTLAND, OREGON
The Oregon
State Police Crime Lab (Portland, Oregon) recently received two unusual
drug submissions from the Portland Police Bureau. The first was a vial of
tan powder (total net mass 3.9 grams), commercially (but crudely) labelled
as "N,N-Dipropyltryptamine" (photo not available). The label also included
the CAS number, warning information, and numbers presumably related to
inventory or production batch. The vial was turned over to the Portland
Police Bureau by the security personnel for an express mail service.
Analysis of the powder by color testing (Webers and PDMAB), GC/MS, FTIR,
and UV gave results consistent with dipropyltryptamine (DPT) (not
quantitated, but only one peak by GC). However, the results were also
consistent with N,N-diisopropyltryptamine (DIPT), and since the laboratory
did not have reference standards for either compound, the identification
was tentative.
The second
submission was a pharmacy-style bottle containing four gel caps, each
containing a small amount of fluffy white crystalline substance (total net
mass of powder less than 10 milligrams), identity unknown but suspected to
be an illicit drug (photo not available). The exhibit was part of a
polydrug seizure from an individual in Portland who was arrested for
failure to appear for previously filed, unrelated drug charges. Analysis
by color testing (Marquis), GC/MS, FTIR, and UV indicated 4-iodo-2,5-
dimethoxyphenethylamine (2C-I).
These were
the first submissions of DPT (DIPT) or 2C-I to the laboratory.
SELECTED REFERENCES
[Notes:
Selected references are a compilation of recent publications of presumed
interest to forensic chemists. Unless otherwise stated, all listed
citations are published in English. If available, the email address for
the primary author is provided as the contact information. Listed mailing
address information (which is sometimes cryptic or incomplete) exactly
duplicates that provided by the abstracting services. In addition, in
order to prevent automated theft of email addresses off the Internet
postings of Microgram Bulletin, unless otherwise requested by the
corresponding author, all email addresses reported in the
Bulletin have had the "@" character replaced by " -at- "; this
will need to be converted back (by hand) before the address can be
used.]
- Borngasser J.
Lab supplies go to the highest bidder: A brief analysis of
clandestine methamphetamine laboratory supplies and methamphetamine
precursors being sold on ebay®. Journal of the Clandestine
Laboratory Investigating Chemists Association 2004;14(2):8. [Editor's
Notes: Presents an overview of the title topic. Note that JCLICA is a
law enforcement restricted journal. Contact: Oregon State Police
Forensic Laboratory, Central Point, OR (street address and zip code not
provided).]
- Dimitroff D.
Psilocybin mushroom cultivation. Journal of the
Clandestine Laboratory Investigating Chemists Association.
2004;14(2):11. [Editor's Notes: Presents an overview of the title topic.
Note that JCLICA is a law enforcement restricted journal. Contact: Peel
Regional Police, Morality Bureau (Drug Unit), Mississauga/Brampton,
Ontario, Canada (street address and Canadian postal zone code not
provided).]
- Person EC, Knops
LA, Northrop DM, Sheridan SP. "One-pot" methamphetamine
manufacture. Journal of the Clandestine Laboratory
Investigating Chemists Association. 2004;14(2):14. [Editor's Notes:
Presents an evaluation of an Internet recipe. Note that JCLICA is a law
enforcement restricted journal. Contact: Washington State Patrol,
Marysville Crime Laboratory, 2700 116th Street NE, Suite P, Marysville,
WA 98271.]
- Galand N, Emouf D,
Montigny F, Dollet J, Pothier J. Separation and identification
of cannabis components by different planar chromatography techniques
(TLC, AMD, OPLC). Journal of Chromatographic Science
2004;42(3):130. [Editor's Notes: Abstract not provided. Contact: N
Garland, Lab Pharmacognosie, UFR Sci Pharmaceut, 31 Ave Monge, F-3720
Tours, France.]
- Pihlainen K,
Kostiainen R. Effect of the eluant on enantiomer separation of
controlled drugs by liquid chromatography - ultraviolet absorbance
detection - electrospray ionisation tandem mass spectrometry using
vancomycin and native beta-cyclodextrin chiral stationary
phases. Journal of Chromatography A 2004;1033(1):91. [Editor's
Notes: Presents the title study on nine amphetamine derivatives (not
specified in abstract), methorphan, and propoxyphene. 14 seized drug
samples (not specified in abstract) were analyzed using the optimized
methodologies. Contact: R Kostiainen, Univ Helsinki, Vikki Drug
Discovery Technol Ctr, POB 56, FIN-00014 Helsinki,
Finland.]
- Van Nimmen NFJ,
Veulemans HAF. Development and validation of a highly sensitive
gas chromatographic - mass spectrometric screening method for the
simultaneous determination of nanogram levels of fentanyl, sufentanil,
and alfentanil in air and surface contamination wipes. Journal
of Chromatography A 2004;1035(2):249. [Editor's Notes: Focus is on
sampling for industrial occupational exposure. Technique uses SIM.
Contact: NFJ Van Nimmen, Katholieke Univ Leuven, Lab Occupat Hyg &
Toxicol, Dept Occupat Environm & Insurance Med, Kapucijnenvoer 35,
6th Floor, B-3000 Louvain, Belgium.]
- Suzuki Y, Arakawa
H, Maeda M. The capillary electrophoresis separation of
benzodiazepine drugs using dextran sulfate and SDS as running
buffer. Biomedical Chromatography 2004;18(3):150. [Editor's
Notes: Presents the EKC analysis of 10 benzodiazepines (not specified in
abstract). The authors claim that the presented method may also be used
for many other pharmaceuticals. Contact: M Maeda, Showa Univ, Sch
Pharmaceut Sci, Shinagawa Ku, Tokyo 1428555, Japan.]
- Sagmuller B,
Schwarze B, Brehm G, Trachta G, Schneider S. Identification of
illicit drugs by a combination of liquid chromatography and
surface-enhanced Raman scattering spectroscopy. Journal of
Molecular Structure 2003;661-662:279. [Editor's Notes: Presents a novel
HPLC-SERS technique for analysis of illicit drugs (not specified in
abstract). Contact: PALM Microlaser Technologies AG, D-82347 Bernried,
Germany.]
- Hajdar M, Ruzdic
E. Characterisation of heroin samples obtained in the area of
the Federation of Bosnia and Herzegovina. Journal of
Environmental Protection and Ecology 2003;4(4):873. [Editor's Notes:
Presents the title survey, using GC/FID analysis to detect 8 opium
alkaloids and 3 typical adulterants. The number of samples and the date
range were not specified in the abstract. Contact: Forensic Department,
Federal Ministry of Internal Affairs, Sarajevo,
Bosnia/Herzegovina.]
- Kite GC, Ismail M,
Simmonds MSJ, Houghton PJ. Use of doubly protonated molecules in
the analysis of cathedulins in crude extracts of khat (Catha edulis) by
liquid chromatography/ serial mass spectrometry. Rapid
Communications in Mass Spectrometry 2003;17(14):1553. [Editor's Notes:
Analysis of fresh khat by LC/MS revealed 62 cathedulins. Contact: Royal
Botanic Gardens, Kew, Richmond, UK TW9 3AB.]
- Jones, JJ, Kidwell
H, Games DE. Application of atmospheric pressure chemical
ionisation mass spectrometry in the analysis of barbiturates by high
speed analytical countercurrent chromatography. Rapid
Communications in Mass Spectrometry 2003;17(14):1565. [Editor's Notes:
The title study was performed on 4 barbiturates (barbital, allobarbital,
phenobarbital, and butalbital). Contact: Mass Spectrometry Research
Unit, University of Wales Swansea, Swansea, UK SA2 8PP.]
- Galimov EM,
Sevast'yanov VS, Kul'bachevskaya EV, Golyavin AA. Determination
of isotopic compositions of carbon and nitrogen by the IRMS method:
Implication for the source of narcotic substance origin.
Doklady Earth Sciences 2003;393(8):1109. [Editor's Notes: Presents the
title study on cocaine and heroin from different regions. Contact:
Vernadsky Institute of Geochemistry and Analytical Chemistry, Russian
Academy of Sciences, Moscow, Russia 119991.]
- Corkery JM, Airs
J. Seizures of drugs in the UK 2001. Home Office
Findings 2003;202:1. [Editor's Notes: Presents a survey of Class A, B,
and C drug seizures made in the U.K. during 2001. Contact: No contact
information was provided.]
- Watanabe S,
Shibata M, Kataoka K. Comparison of data obtained by various GC
methods for impurity profiling of stimulant drugs. Kanzei Chuo
Bunsekishoho 2002;42:73. [Editor's Notes: Three different GC methods
were used for impurity profiling of 10 typical impurities in 12 samples
of stimulant drugs (not specified in abstract). This article is written
in Japanese. Contact: Central Customs Laboratory, Ministry of Finance,
Chiba, Japan 277-0882.]
Additional References of Possible Interest:
- Meatherall R,
Sharma P. Foxy, a designer tryptamine hallucinogen.
Journal of Analytical Toxicology 2003;27(5):313. [Editor's Notes:
Primary focus is analysis of biological fluids; however, includes a
small scale mass spectra (from GC/MS) of "Foxy"
(5-methoxy-N,N-diisopropyltryptamine). Contact: R Meatherall, St
Boniface Gen Hosp, Lab Med, 409 Tache Ave, Wiinipeg, MB R2H 2A6,
Canada.]
- Curtis B, Kemp P,
Harty L, Choi C, Christensen D. Postmortem identification and
quantitation of 2,5-dimethoxy-4-n-propylthiophenethylamine using GC-MSD
and GC-NPD. Journal of Analytical Toxicology 2003;27(7):493.
[Editor's Notes: Primary focus is analysis of biological fluids and
tissue samples; however, includes a small scale mass spectra (from
GC/MS) of the title compound (i.e., 2C-T-7). Contact: Office of the
Chief Medical Examiner, 901 N. Stonewall, Oklahoma City, OK
73117.]
- Zhang S, Zhuang
YF, Ju HX. Flow-injection chemiluminescence determination of
papaverine using cerium(IV)-sulfite system. Analytical Letters
2004;37(1):143. [Editor's Notes: The title study is presented; the
method is adequate for determination of papaverine in pharmaceuticals
and in biological fluids. Contact: HX Ju, Nanjing Univ, Dept Chem, Inst
Analyt Sci, State Key Lab Coordinat Chem, Nanjing 210093, Peoples R
China.]
- Vas G, Vekey K.
Solid-phase microextraction: A poweful sample preparation tool
prior to mass spectrometric analysis. Journal of Mass
Spectrometry 2004;39(3):233. [Editor's Notes: Presents an overview and
review of SPME. Contact: G Vas, Univ Antwerp, Dept Biomed Mass
Spectrometry, Univ Plein 1, B-2610 Wilrijk, Belgium.]
- Derringer B, Leigh
T. Solving problems in ion mobility measurements of forensic
samples with thermal desorption and dynamic modeling. Diss
Abstr Int B 2003;64(4):1715. [Editor's Notes: No abstract provided.
Contact: Ohio Univ, Athens, OH (no further addressing information
provided.]
- Schaefer T.
Chemists in criminal technology. Nachrichten aus der
Chemie 2004;52(2):223. [Editor's Notes: A mini-review covering
criminalists and forensic chemists. This article is written in German.
Contact: Wiesbaden, Germany (no other addressing information was
provided.]
- Nguyen DH, Berry
S, Geblewicz JP, Couture G, Huynh P. Chemiluminescent detection
of explosives, narcotics, and other chemical substances. U.S.
Pat. Appl. Publ. US 20040053421 A1 18 Mar 2004. CLASS: ICM: G01N021-76.
NCL: 436172000;436164000; 436117000; 436155000; 436159000; 422052000;
422078000; 422080000;422082050; 422082080. APPLICATION: US 2002-241407
12 Sep 2002. [Editor's Notes: Presents the title patent. Narcotics not
specified in abstract. Contact: Can. (no further addressing information
was provided).]
- Brestel M, Gft M,
Sharon U. Controlled substance detection and identification
system. U.S. Pat. Appl. Publ. US 20040051867 A1 18 Mar 2004.
CLASS: ICM: G01J003-44. ICS: G01J003-30. NCL: 356318000; 356301000.
APPLICATION: US 2003-428398 2 May 2003. PRIORITY: IL 2002-151745 12 Sep
2002. [Editor's Notes: Presents the title patent. Controlled substances
not specified in abstract. Contact: International Technologies (Lasers)
Ltd., Israel (no further addressing information was
provided).]
- Zhang H, Tang J,
Liu Y, Shao W, Fan X, Qin Y. Method and test paper for
semi-quantitative detection of drugs/medicine by color band-degressive
immunological chromatography. Faming Zhuanli Shenqing Gongkai
Shuomingshu CN 1,381,729 (Cl. G01N33/558), 27 Nov 2002, Appl.
2,002,114,110, 30 Apr 2002. [Editor's Notes: The title methodology was
applied to over 24 drugs. This patent is written in Chinese. Contact:
Changsa Mental Disease Hospital, Peop. Rep. China.]
| Virtual Processing |
by: Michael J. Phelan DEA Digital
Evidence Laboratory |
Virtual processing is
the simulation of a computer operating system or application program
within a real world computer under the control of the host computer's
operating system. Virtual processing enables multiple applications to
operate in an isolated operating system environment. It also
compartmentalizes processes, and can therefore minimize program failures
that can stop an entire computer system.
To date, virtual
processing has been primarily used in main frame computers, but not with
personal computers, due to limitations with PC hardware and operating
system architectures. Virtual processing requires extensive computing
resources, including fast processor speeds, robust operating system
architectures (that support multiple concurrent processing), and fast
computer memory management. However, recent advances in these technologies
have increased its potential for use in PC's, including for digital
evidence examination purposes. In the latter case, potential benefits
include reduced examination times and fewer examination
computers.
The principal benefit
of virtual processing is eliminating the need to run concurrent computer
systems in order to view certain types of data. Most digital evidence
forensics are conducted using a "forensic platform" such as Access Data's
Forensic Tool Kit (FTK), Guidance Software's Encase, or the U.S.
Government's Ilook licensed software. These platforms use standard data
recovery techniques such as erased file recovery or keyword searching, and
are highly effective with routine programs and files. However, there is
often a need to run specialized programs in order to view proprietary
types of binary data, especially where the data is not stored in a
standard ASCII format (that is, that common file browsers can interpret
and display). Applications such as financial accounting data and pharmacy
transactional data frequently utilize proprietary data storage formats
that cannot be viewed using any of the standard digital evidence forensic
examination platforms.
In other instances,
the ability to view the desktop display of a computer helps the examiner
identify the application programs that are important to the computer user.
For example, short cuts to ISP's (AOL, MSN, Hotmail, or Yahoo), or
frequently used applications such as Quicken, or critical data files such
as an Excel spreadsheet. Recovery of these data types requires that a
bootable work copy of the hard drive be created in order to run the user's
operating system and/or application software.
Virtual processing
offers the potential to eliminate the extra steps involved in creating and
mounting such bootable work copies. It can take a day or more to create
and successfully mount such copies in a different computer hardware
environment ? a very significant amount of time for any
examiner.
Application of
virtual processing to the examination of digital evidence is therefore an
important evolutionary advance. To date, there have been five such
advances, as follows:
Generation
One Initially, digital evidence was regarded as a static
collection of digital data files or fragments of user or computer system
generated data. This static data was viewed as objects that could be
viewed (browsed) or searched using text string search engines. Use of
digital evidence forensic tools permitted analysis without changing any of
the data. This has always been a digital evidence forensic best practice.
Generation
Two The second generation of digital evidence forensic
techniques improved on the initial, purely static examination approach by
utilizing enhanced technical evidence duplication capabilities to create
bootable work copies. Reviews are conducted by running a copy of the
user's operating system and/or application program. Creating a bootable
work copy is a well accepted digital evidence forensic practice that
supplements static browsing and keyword searching. However, the technique
is limited to viewing application output only, because it changes some
file date/time stamps, and also overwrites data in the temporary work
files that are managed by the operating system. Therefore, a completely
separate examination of a second work copy is often necessary to browse
and keyword search other areas of the evidence. This can result in a
lengthy examination process.
Generation
Three The third generation of evidence copying technology is
known as "imaging". Images are files that can be mounted within a "digital
evidence forensic platform". The image files contain an accurate
representation of the original evidence, as well as embedded data required
for data authentication purposes. In contrast to bootable work copies,
image files are not hardware dependent. However, digital evidence
examination of images is limited to viewing data in a format that
precludes assessment of the user's desktop, or the running of application
programs. This can be a significant problem in certain types of cases
where the computer user's most commonly accessed programs and/or files are
displayed on the desktop, or where specialized programs are needed to
access data (for example, financial accounting software frequently needs
to be run in order to fully understand data stored in credit and debit
columns).
Generation
Four The fourth generation consists of "emulation" technology,
which is an application program that gives the appearance that a computer
is operating within a computer. One simple example of an emulation program
is the use of a Microsoft DOS command line prompt from within a Microsoft
Windows operating system (such as Win 95/98). While it appears that any
program operating from the DOS prompt is a computer within the Windows
95/98 computer, it is actually a WIN 95/98 operating system program giving
that appearance.
A second, well known
emulation program is the original Microsoft Windows program named "Windows
for Work Groups". As installed on the old Intel 286 computers, this
program gave the appearance and feel of Windows, but it was actually a DOS
program. It wasn't until Windows 95 was introduced by Microsoft that a
true Windows operating system was available to Microsoft software
users.
Emulation technology
has little substantive benefit in digital evidence examinations. However,
it is an important concept in understanding the evolution of computer
processing from single dedicated machines to virtual
processing.
Generation
Five The fifth and most recent generation of digital evidence
forensic technology involves virtual processing wherein a computer
actually operates within a computer (that is, not a simulation, but rather
in reality). Virtual processing provides the examiner with a choice of
utilizing traditional static data recovery techniques while running either
the operating system (to view the desktop) or select application programs
(to view proprietary binary data and understand the significance of
specialized application programs). Virtual processing only involves
manipulation of the image file in the computer memory, thereby eliminating
the problem of changing file date/time stamp information or temporary work
areas associated with the operating system.
Continued technology
advances (such as virtual image processing) are an efficient means to
examine data both statically and dynamically, without having to produce
two evidentiary work copies. Thus, the technique reduces the need for an
additional examiner computer or the concurrent additional examiner time
needed to make the second copy. This saves both resources and time, two
precious commodities in most digital evidence laboratories.
<Published by the Drug Enforcement Administration
Office of Forensic Sciences Washington, D.C. 20537
The U. S. Attorney General has
determined that the publication of this periodical is necessary in the
transaction of the public business required by the Department of Justice.
Information, instructions, and disclaimers are published in the January
issues.
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